| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on late protein activity in tumor tissue |
Western Blot |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on tumor growth |
Histological staining |
30.00 mg/kg |
KCNR (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on tumor growth |
Histological staining |
30.00 mg/kg |
SY5Y (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on tumor growth |
Histological staining |
30.00 mg/kg |
Rh18 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on tumor growth |
Histological staining |
30.00 mg/kg |
TC32 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
0.50 µM |
MO4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
0.50 µM |
K1735-C4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
0.50 µM |
1087-mel |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
1.00 µM |
MO4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
1.00 µM |
K1735-C4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
1.00 µM |
1087-mel |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
5.00 µM |
MO4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
5.00 µM |
K1735-C4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
5.00 µM |
1087-mel |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
10.00 µM |
MO4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
10.00 µM |
K1735-C4 |
Mus musculus |
|
|
|
| AZD1480 |
Influence on apoptosis |
Flow cytometry- annexin V staining |
10.00 µM |
1087-mel |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
MO4 |
Mus musculus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
MO4 |
Mus musculus |
|
p-STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
MO4 |
Mus musculus |
|
p-STAT3 |
|
