| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft MC1 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 4913 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 3863 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 4272 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 3904 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 4195 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 2147 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft T47D |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft MCF7 |
Mus musculus |
SCID/Beige nude mice |
p-STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
2.50 µM |
786-O |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
5.00 µM |
786-O |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
786-O |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
2.50 µM |
PNX0010 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
5.00 µM |
PNX0010 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
PNX0010 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
10.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
20.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity |
Western Blot |
40.00 µM |
MKN45 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
0.10 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
0.30 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
1.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
3.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
10.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
30.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Confocal and high-throughput fluorescence microscopy (HTFM) |
100.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
0.10 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
0.30 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
1.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
3.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
10.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
30.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein translocation in presence of IL-6 |
Fluorescence intensity in the nucleus (FLIN) |
100.00 µM |
Stat3−/− MEF |
Mus musculus |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.10 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
1.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
3.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
30.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
100.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.10 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
0.30 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
30.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on protein activity (with and without ligand) |
Luminex assay |
100.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 4400 |
Mus musculus |
SCID/Beige nude mice |
STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 4849 |
Mus musculus |
SCID/Beige nude mice |
STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 3613B |
Mus musculus |
SCID/Beige nude mice |
STAT3 |
|
| Piperlongumine |
Influence on cell apoptosis |
Luminex assay |
30.00 µM |
patient derived xenograft 3824 |
Mus musculus |
SCID/Beige nude mice |
STAT3 |
|
