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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Withacnistin Infleunce on protein translocation in presence of EGF Immunofluorescence 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein transcriptiona activity Luciferse activity 1.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 1.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 1.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 1.00 µM A549 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 3.00 µM A549 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 5.00 µM A549 Homo sapiens
Withacnistin Influence on cell motility Colony formation assay 10.00 µM A549 Homo sapiens
Withacnistin Influence on cell apoptosis TUNEL 0.10 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell apoptosis TUNEL 0.30 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell apoptosis TUNEL 1.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell apoptosis TUNEL 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on cell apoptosis TUNEL 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on tumor growth Tumor volume 20.00 mg/kg MDA-MB-468(xenograft) Mus musculus ErbB2