Investigated event: Influence on tumor growth

Name Value
Compound Withacnistin
Investigated event Influence on tumor growth
Experiment type Tumor volume
Concentration 20.00 mg/kg
Cell line MDA-MB-468(xenograft)
Organism Mus musculus
Animal model ErbB2
STAT protein
Other
Reference
Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. British journal of cancer X Zhang, M A Blaskovich, K D Forinash, S M Sebti, 111, 5, 2014-08-26, 2014-07-01, 10.1038/bjc.2014.349 DOI: 10.1038/bjc.2014.349 PUBMED: 24983364 PMCID: PMC4150266