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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 1.00 µM TF-1 Homo sapiens
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 3.00 µM TF-1 Homo sapiens
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 0.10 µM U266 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 0.30 µM U266 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 1.00 µM U266 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 3.00 µM U266 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 10.00 µM U266 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 0.10 µM U266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 0.30 µM U266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 1.00 µM U266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 3.00 µM U266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 10.00 µM U266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 0.10 µM U266 Homo sapiens
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 0.30 µM U266 Homo sapiens
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 1.00 µM U266 Homo sapiens
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 3.00 µM U266 Homo sapiens
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 10.00 µM U266 Homo sapiens
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.10 µM NIH 3T3 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.30 µM NIH 3T3 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 1.00 µM NIH 3T3 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 3.00 µM NIH 3T3 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH 3T3 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.10 µM NIH 3T3 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.30 µM NIH 3T3 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 1.00 µM NIH 3T3 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 3.00 µM NIH 3T3 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH 3T3 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.10 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.30 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 1.00 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 3.00 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH 3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.10 µM NIH 3T3 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.30 µM NIH 3T3 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 1.00 µM NIH 3T3 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 3.00 µM NIH 3T3 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH 3T3 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.10 µM NIH 3T3 Homo sapiens
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 0.30 µM NIH 3T3 Homo sapiens
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 1.00 µM NIH 3T3 Homo sapiens
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 3.00 µM NIH 3T3 Homo sapiens
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH 3T3 Homo sapiens
Withacnistin Influence on protein-DNA interaction in presence of EGF Immunofluorescence 3.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein-DNA interaction in presence of EGF Immunofluorescence 5.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein-DNA interaction in presence of EGF Immunofluorescence 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein-DNA interaction in presence of EGF Immunofluorescence 3.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein-DNA interaction in presence of EGF Immunofluorescence 5.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein-DNA interaction in presence of EGF Immunofluorescence 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on expression of proteins downstream target genes Western Blot 3.00 µM MDA-MB-468 Homo sapiens p-STAT3