Investigated event: Influence on protein-DNA interaction in presence of EGF

Name Value
Compound Withacnistin
Investigated event Influence on protein-DNA interaction in presence of EGF
Experiment type Immunofluorescence
Concentration 3.00 µM
Cell line MDA-MB-468
Organism Homo sapiens
Animal model
STAT protein p-STAT3
Other
Reference
Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. British journal of cancer X Zhang, M A Blaskovich, K D Forinash, S M Sebti, 111, 5, 2014-08-26, 2014-07-01, 10.1038/bjc.2014.349 DOI: 10.1038/bjc.2014.349 PUBMED: 24983364 PMCID: PMC4150266