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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Cucurbitacin E Influence on cell apoptosis Flow cytometry 0.50 nM PC3
Cucurbitacin E Influence on cell apoptosis Flow cytometry 1.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on cell apoptosis Flow cytometry 10.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on tumor growth Tumor weight 3.00 mg/kg PC3(xenograft) Mus musculus c57BL/6
Cucurbitacin E Influence on tumor growth Tumor volume 3.00 mg/kg PC3(xenograft) Mus musculus c57BL/6
Cucurbitacin E Influence on tumor growth Body weight 3.00 mg/kg PC3(xenograft) Mus musculus c57BL/6
Cucurbitacin E Influence on tumor angiogenesis Immunohistochemistry 3.00 mg/kg PC3(xenograft) Mus musculus c57BL/6
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens p-STAT3
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens p-STAT3
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens p-STAT3
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens p-STAT3
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens STAT3
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens STAT3
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens STAT3
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens STAT3
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens STAT3(nuclear)
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens STAT3(nuclear)
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens STAT3(nuclear)
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens STAT3(nuclear)
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens STAT3(cytoplasmic)
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens STAT3(cytoplasmic)
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens STAT3(cytoplasmic)
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens STAT3(cytoplasmic)
Cucurbitacin E Influence on protein activity Western Blot 0.01 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 0.10 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 1.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Western Blot 10.00 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Chromatin immunoprecipitation assay 0.01 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Chromatin immunoprecipitation assay 0.10 nM PC3 Homo sapiens
Cucurbitacin E Influence on protein activity Chromatin immunoprecipitation assay 1.00 nM PC3 Homo sapiens