Investigated event: Influence on tumor angiogenesis

Name Value
Compound Cucurbitacin E
Investigated event Influence on tumor angiogenesis
Experiment type Immunohistochemistry
Concentration 3.00 mg/kg
Cell line PC3(xenograft)
Organism Mus musculus
Animal model c57BL/6
STAT protein
Other
Reference
Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway. Carcinogenesis Yanmin Dong, Binbin Lu, Xiaoli Zhang, Jing Zhang, Li Lai, Dali Li, Yuanyuan Wu, Yajuan Song, Jian Luo, Xiufeng Pang, Zhengfang Yi, Mingyao Liu, 31, 12, None, 2010-08-23, 10.1093/carcin/bgq167 DOI: 10.1093/carcin/bgq167 PUBMED: 20732905 PMCID: 20732905