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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 1.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 3.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 5.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 1.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 3.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 5.00 µM A2058 Homo sapiens STAT3