| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT5A |
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
IP: EGFR IB: STAT3 |
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
IP: EGFR IB: STAT5 |
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
U266 |
Homo sapiens |
|
IP: GP130 IB: STAT3 |
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
U266 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
U266 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
RPMI-8226 |
Homo sapiens |
|
IP: GP130 IB: STAT3 |
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
RPMI-8226 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity |
Co-immunoprecipitation |
10.00 µM |
RPMI-8226 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
p-STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity in presence of GMCSF |
Western Blot |
10.00 µM |
TF-1 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of GMCSF |
Western Blot |
10.00 µM |
TF-1 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of GMCSF |
Western Blot |
10.00 µM |
TF-1 |
Homo sapiens |
|
p-STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of GMCSF |
Western Blot |
10.00 µM |
TF-1 |
Homo sapiens |
|
STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of GMCSF |
Western Blot |
10.00 µM |
TF-1 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity in presence of IFNβ |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of IFNβ |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of IFNβ |
Western Blot |
10.00 µM |
U266 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity in presence of PDGF-BB |
Western Blot |
10.00 µM |
NIH 3T3 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of PDGF-BB |
Western Blot |
10.00 µM |
NIH 3T3 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of PDGF-BB |
Western Blot |
10.00 µM |
NIH 3T3 |
Homo sapiens |
|
p-STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of PDGF-BB |
Western Blot |
10.00 µM |
NIH 3T3 |
Homo sapiens |
|
STAT5 |
|
| Withacnistin |
Influence on protein activity in presence of PDGF-BB |
Western Blot |
10.00 µM |
NIH 3T3 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein-DNA interaction in presence of EGF |
Immunofluorescence |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein-DNA interaction in presence of EGF |
Immunofluorescence |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT5 |
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT5 |
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Luciferase activity |
10.00 µM |
MDA-MB-468 pLucSRE |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on expression of proteins downstream target genes |
Luciferase activity |
10.00 µM |
MDA-MB-468 pLucTKS3 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on cell apoptosis |
TUNEL |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on cell motility |
Invasion assay |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on cell motility |
Colony formation assay |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
|
|
