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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Withacnistin Influence on cell motility Colony formation assay 10.00 µM A549 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens IP:EGFR IB:STAT3
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens IP:EGFR IB:STAT5
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity Co-immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens IP:GP130 IB:STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM U-266 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens IP:GP130 IB:STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Co-immunoprecipitation 10.00 µM RPMI-8226 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM U-266 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM U-266 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM U-266 Homo sapiens
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM U-266 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of EGF Western Blot 10.00 µM U-266 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of GMCSF Western Blot 10.00 µM TF-1 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 10.00 µM TF-1 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 10.00 µM TF-1 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of IFNβ Western Blot 10.00 µM TF-1 Homo sapiens
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH3T3 Homo sapiens
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH3T3 Homo sapiens p-STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH3T3 Homo sapiens STAT5
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH3T3 Homo sapiens p-STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH3T3 Homo sapiens STAT3
Withacnistin Influence on protein activity in presence of PDGF-BB Western Blot 10.00 µM NIH3T3 Homo sapiens
Withacnistin Infleunce on protein translocation in presence of EGF Immunofluorescence 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Infleunce on protein translocation in presence of EGF Immunofluorescence 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein transcriptiona activity Luciferse activity 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein transcriptiona activity Luciferse activity 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT3
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT5
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Withacnistin Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens