| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of TGF-β and IL-6 |
Western Blot |
10.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of TGF-β and IL-6 |
Western Blot |
30.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of TGF-β and IL-6 |
Western Blot |
100.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
30.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
100.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
300.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
30.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
100.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
300.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
1000.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
30.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
100.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
300.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of TNF |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of TGF-β and IL-6 |
Western Blot |
10.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of TGF-β and IL-6 |
Western Blot |
30.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of TGF-β and IL-6 |
Western Blot |
100.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
30.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
100.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
300.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
30.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
100.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
300.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of TNF |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
