Investigated event: Influence on protein acticity in presence of IL-6
| Name | Value |
|---|---|
| Compound | Tofacitinib (CP-690.550) |
| Investigated event | Influence on protein acticity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 30.00 nM |
| Cell line | FLS |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 |
| Other |
Reference
The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon. Annals of the rheumatic diseases Sanna Rosengren, Maripat Corr, Gary S Firestein, David L Boyle, 71, 3, None, 2011-11-25, 10.1136/ard.2011.150284
DOI: 10.1136/ard.2011.150284
PUBMED: 22121136
PMCID: 22121136