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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
OPB-31121 Influence on tumor growth Tumor volume 30.00 mg/kg SNU484 (xenograft) Mus musculus SCID mice
OPB-31121 Influence on tumor growth Tumor volume 60.00 mg/kg SNU484 (xenograft) Mus musculus SCID mice
OPB-31121 Influence on tumor growth Tumor volume 100.00 mg/kg SNU484 (xenograft) Mus musculus SCID mice
OPB-31121 Influence on tumor growth Tumor volume 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice
OPB-31121 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice p-STAT3 (Y705)
OPB-31121 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice STAT3
OPB-31121 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice
OPB-31121 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice
OPB-31121 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice
OPB-31121 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice
OPB-31121 Influence on cell apoptosis TUNEL 5.00 mg/kg HCT116 (xenograft) Mus musculus nude mice STAT3