| OPB-31121 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
DLD1 |
Homo sapiens |
|
p-STAT1 (Y701) |
|
| OPB-31121 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
DLD1 |
Homo sapiens |
|
STAT1 |
|
| OPB-31121 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
Hep3B |
Homo sapiens |
|
p-STAT1 (Y701) |
|
| OPB-31121 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
Hep3B |
Homo sapiens |
|
STAT1 |
|
| OPB-31121 |
Influence on cell viability |
MTT |
5.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
5.00 µM |
DLD1 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
5.00 µM |
SW480 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
5.00 µM |
Huh7 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
5.00 µM |
7721 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell proliferation |
Colony formation assay |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell proliferation |
Colony formation assay |
5.00 µM |
Huh7 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell motility |
Wound healing assay |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell motility |
Wound healing assay |
5.00 µM |
Huh7 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on protein translocation |
Immunofluorescence |
5.00 µM |
DLD1 |
Homo sapiens |
|
STAT3 |
|
| OPB-31121 |
Influence on protein translocation |
Immunofluorescence |
5.00 µM |
Hep3B |
Homo sapiens |
|
STAT3 |
|
| OPB-31121 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
p-STAT3 (Y705) |
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
STAT3 |
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on cell apoptosis |
TUNEL |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
STAT3 |
|
