| Fraxetin |
Influence on cell apoptosis |
CCK8 assay |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
CCK8 assay |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
CCK8 assay |
20.00 µM |
NCM460 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell proliferation |
Colony formation assay |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell proliferation |
Colony formation assay |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Flow cytometry- annexin V binding and propidium iodide staining |
20.00 µM |
COAD |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell cycle |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
RT-qPCR |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
RT-qPCR |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
RT-qPCR |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
RT-qPCR |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell apoptosis |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
STAT3 |
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
STAT3 |
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
p-STAT3 |
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
p-STAT3 |
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on protein activity |
Western Blot |
20.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Average mice weight |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Tumor volume |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Tumor weight |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Immunohistochemistry |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Immunohistochemistry |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Immunohistochemistry |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Immunohistochemistry |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on cell proliferation in tumor tissue |
Immunohistochemistry |
20.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on protein activity in tumor tissue |
Western Blot |
20.00 mg/kg |
COAD (xenograft) |
Mus musculus |
BALB/c |
|
|
| Fraxetin |
Influence on protein activity in tumor tissue |
Western Blot |
20.00 mg/kg |
COAD (xenograft) |
Mus musculus |
BALB/c |
|
|
