Investigated event: Influence on cell proliferation in tumor tissue
| Name | Value |
|---|---|
| Compound | Fraxetin |
| Investigated event | Influence on cell proliferation in tumor tissue |
| Experiment type | Immunohistochemistry |
| Concentration | 20.00 mg/kg |
| Cell line | HCT116 (xenograft) |
| Organism | Mus musculus |
| Animal model | BALB/c |
| STAT protein | |
| Other | Cleaved PARP |
Reference
Fraxetin inhibits the growth of colon adenocarcinoma cells via the Janus kinase 2/signal transducer and activator of transcription 3 signalling pathway. The international journal of biochemistry & cell biology Shuo Ren, Yanwei Xing, Chengbo Wang, Fengqi Jiang, Guangyu Liu, Ziyi Li, Tao Jiang, Yuekun Zhu, Daxun Piao, 125, None, None, 2020-06-03, 10.1016/j.biocel.2020.105777
DOI: 10.1016/j.biocel.2020.105777
PUBMED: 32504672
PMCID: 32504672