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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-2 Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 5.00 µM U251 SHP-2 Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 TC-PTP Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-1 Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in tumor tissue Immunohistochemistry 30.00 mg/kg U87 (xenograft) Mus musculus BALB/c p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in tumor tissue Immunohistochemistry 60.00 mg/kg U87 (xenograft) Mus musculus BALB/c p-STAT3(Y705)