Investigated event: Influence on protein activity in tumor tissue

Name Value
Compound Cryptotanshinone
Investigated event Influence on protein activity in tumor tissue
Experiment type Immunohistochemistry
Concentration 60.00 mg/kg
Cell line U87 (xenograft)
Organism Mus musculus
Animal model BALB/c
STAT protein p-STAT3(Y705)
Other
Reference
Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation. Cell death & disease Liang Lu, Sulin Zhang, Cuixian Li, Chun Zhou, Dong Li, Peiqing Liu, Min Huang, Xiaoyan Shen, 8, 5, 2017-05-11, 2017-05-11, 10.1038/cddis.2017.174. DOI: 10.1038/cddis.2017.174. PUBMED: 28492557 PMCID: PMC5520699