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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 20.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 1.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 2.50 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 5.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 10.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 20.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 1.00 µM EC109 Homo sapiens p-STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 2.50 µM EC109 Homo sapiens p-STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 5.00 µM EC109 Homo sapiens p-STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 10.00 µM EC109 Homo sapiens p-STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 20.00 µM EC109 Homo sapiens p-STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 1.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 2.50 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 5.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 10.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 20.00 µM EC109 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 1.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 2.50 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 5.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 10.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of IL-6 Western Blot 20.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 25.00 mg/kg EC109 (xenograft) Mus musculus BALB/c p-STAT3
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg EC109 (xenograft) Mus musculus BALB/c p-STAT3
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 25.00 mg/kg EC109 (xenograft) Mus musculus BALB/c STAT3
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg EC109 (xenograft) Mus musculus BALB/c STAT3
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 25.00 mg/kg EC109 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg EC109 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 25.00 mg/kg EC109 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg EC109 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on cell apoptosis Western Blot 15.00 µM SGC7901 Homo sapiens
Cryptotanshinone Influence on cell apoptosis Western Blot 15.00 µM SGC7901 Homo sapiens
Cryptotanshinone Influence on cell apoptosis Western Blot 15.00 µM SGC7901 Homo sapiens
Cryptotanshinone Influence on cell apoptosis Western Blot 15.00 µM SGC7901 Homo sapiens
Cryptotanshinone Influence on cell apoptosis Western Blot 15.00 µM SGC7901 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM SGC7901 Homo sapiens p-STAT3 (Tyr705)
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM MKN45 Homo sapiens p-STAT3 (Tyr705)
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM HGC27 Homo sapiens p-STAT3 (Tyr705)
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM SGC7901 Homo sapiens p-STAT3 (Ser727)
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM MKN45 Homo sapiens p-STAT3 (Ser727)
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM HGC27 Homo sapiens p-STAT3 (Ser727)
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM SGC7901 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM MKN45 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM HGC27 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM SGC7901 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM MKN45 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 15.00 µM HGC27 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM SGC7901 Homo sapiens p-STAT3 (Tyr705)
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM SGC7901 Homo sapiens p-STAT3 (Tyr705)
Cryptotanshinone Influence on protein activity Western Blot 7.50 µM SGC7901 Homo sapiens p-STAT3 (Tyr705)
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM SGC7901 Homo sapiens p-STAT3 (Tyr705)