| Brevilin A |
Influence on STAT3 signalling |
Western Blot |
12.50 µM |
A549R |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on STAT3 signalling |
Western Blot |
25.00 µM |
A549R |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on constitutive STAT3 activation |
Western Blot |
5.00 µM |
DU145 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on constitutive STAT3 activation |
Western Blot |
10.00 µM |
DU145 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on constitutive STAT3 activation |
Western Blot |
15.00 µM |
DU145 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on constitutive STAT3 activation |
Western Blot |
5.00 µM |
MDA-MB-468 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on constitutive STAT3 activation |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on constitutive STAT3 activation |
Western Blot |
15.00 µM |
MDA-MB-468 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein upon cytokine treatment |
Western Blot |
10.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein upon cytokine treatment |
Western Blot |
10.00 µM |
Hela |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein upon cytokine treatment |
Western Blot |
10.00 µM |
HepG2 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2-JH1 overexpressed protein |
Western Blot |
10.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2-JH1 overexpressed protein |
Western Blot |
15.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein overexpression |
Western Blot |
15.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein overexpression |
Western Blot |
15.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein overexpression |
Western Blot |
15.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein overexpression |
Western Blot |
15.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on kinase activity (kinase assay) Tyk2-JH1 kinase domain |
Western Blot |
10.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on kinase activity (kinase assay) Tyk2-JH1 kinase domain |
Western Blot |
20.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on kinase activity (kinase assay) Tyk2-JH1 kinase domain |
Western Blot |
40.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on kinase activity (kinase assay) Tyk2-JH1 kinase domain |
Western Blot |
80.00 µM |
HEK293T |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
5.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
7.50 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
5.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
7.50 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
5.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
7.50 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
5.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
7.50 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein levels in tumor tissue |
Western Blot |
4.50 mg/kg |
A375 |
Mus musculus |
|
pTyr705-STAT3 |
|
