| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK1-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
5.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
7.50 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
5.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
7.50 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (JAK3-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
5.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
7.50 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
10.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
12.50 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
15.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
17.50 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Measurement of IC50 value JAKs-JH1 truncated kinases |
Western Blot |
20.00 µM |
HEK293T (Tyk2-JH1) |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein levels in tumor tissue |
Western Blot |
4.50 mg/kg |
A375 |
Mus musculus |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on protein levels in tumor tissue |
Western Blot |
9.00 mg/kg |
A375 |
Mus musculus |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2/STAT3 signalling in melanoma cells |
Western Blot |
1.00 µM |
A375 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2/STAT3 signalling in melanoma cells |
Western Blot |
2.00 µM |
A375 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2/STAT3 signalling in melanoma cells |
Western Blot |
3.00 µM |
A375 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2/STAT3 signalling in melanoma cells |
Western Blot |
1.00 µM |
A2058 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2/STAT3 signalling in melanoma cells |
Western Blot |
2.00 µM |
A2058 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on JAK2/STAT3 signalling in melanoma cells |
Western Blot |
3.00 µM |
A2058 |
Homo sapiens |
|
pTyr705-STAT3 |
|
| Brevilin A |
Influence on STAT3 nuclear localization |
Western Blot |
1.00 µM |
A375 |
Homo sapiens |
|
STAT3 (cytoplasmic) |
|
| Brevilin A |
Influence on STAT3 nuclear localization |
Western Blot |
2.00 µM |
A375 |
Homo sapiens |
|
STAT3 (cytoplasmic) |
|
| Brevilin A |
Influence on STAT3 nuclear localization |
Western Blot |
3.00 µM |
A375 |
Homo sapiens |
|
STAT3 (cytoplasmic) |
|
| Brevilin A |
Influence on STAT3 nuclear localization |
Western Blot |
1.00 µM |
A2058 |
Homo sapiens |
|
STAT3 (cytoplasmic) |
|
| Brevilin A |
Influence on STAT3 nuclear localization |
Western Blot |
2.00 µM |
A2058 |
Homo sapiens |
|
STAT3 (cytoplasmic) |
|
| Brevilin A |
Influence on STAT3 nuclear localization |
Western Blot |
3.00 µM |
A2058 |
Homo sapiens |
|
STAT3 (cytoplasmic) |
|
