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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BP-1-102/ 17o Influence on proliferation Proliferaion Assay 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on proliferation Proliferaion Assay 5.00 µM Burktte Mus musculus
BP-1-102/ 17o Influence on proliferation Proliferaion Assay 5.00 µM Jurkat T-ALL Mus musculus
BP-1-102/ 17o Influence on tumor growth Individual tumor size 3.00 mg/kg REH tumor Mus musculus
BP-1-102/ 17o Influence on tumor growth Mean tumor size 3.00 mg/kg REH tumor Mus musculus
BP-1-102/ 17o Influence on protein Western Blot 5.00 µM REH-B-ALL Mus musculus p-STAT3
BP-1-102/ 17o Influence on protein Western Blot 5.00 µM REH-B-ALL Mus musculus STAT3
BP-1-102/ 17o Influence on gene expression RT-qPCR 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 5.00 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on gene expression RT-qPCR 2.50 µM REH-B-ALL Mus musculus
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 10.00 µM -/-MEFs Mus musculus
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 20.00 µM -/-MEFs Mus musculus
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 30.00 µM -/-MEFs Mus musculus
BP-1-102/ 17o Antitumor effect Tumor size 1.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
BP-1-102/ 17o Antitumor effect Tumor size 3.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
BP-1-102/ 17o Antitumor effect Tumor size 3.00 mg/kg A2058 (xenograft) Mus musculus