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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BBMD3 (berbamine derivative) Cell viability MTS Assay 0.50 µM NHDF Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on apoptosis Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on apoptosis Western Blot 0.50 µM A2058 Homo sapiens