| Tocilizumab |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
p-STAT3 |
|
| Tocilizumab |
Influence on tumor growth |
Mouse weight |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
STAT3 |
|
| Tocilizumab |
Influence on tumor growth |
Survival Rate |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on tumor growth |
Microvessel density staining |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
1.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
10.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell cycle |
Flow cytometry |
1.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell cycle |
Flow cytometry |
10.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
p-STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
p-STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
p-STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of rhIL-6 |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
p-STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
p-STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
p-STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
STAT3 |
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.10 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.00 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on protein activity in presence of conditionend medium |
Western Blot |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
