3,3 diindolylmethane |
Influence on protein translocation |
Western Blot |
25.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein translocation |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein translocation |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein-DNA interaction |
Luciferase activity |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
STAT3 |
|
3,3 diindolylmethane |
Influence on protein activity in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
3,3 diindolylmethane |
Influence on protein activity in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
STAT3 |
|
3,3 diindolylmethane |
Influence on protein activity in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein activity in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein activity in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein activity in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein activity in cells overexpressing STAT3 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
3,3 diindolylmethane |
Influence on protein activity in cells overexpressing STAT3 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
p-STAT3 (S727) |
|
3,3 diindolylmethane |
Influence on protein activity in cells overexpressing STAT3 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
STAT3 |
|
3,3 diindolylmethane |
Influence on protein activity in cells overexpressing STAT3 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein activity in cells overexpressing STAT3 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein activity in cells overexpressing STAT3 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell apoptosis in presence of IL-6 |
Flow cytometry- annexin V binding and propidium iodide staining |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on apoptosis in cells overexpressing STAT3 |
Flow cytometry- annexin V binding and propidium iodide staining |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Infleunce on cytokine secretion |
ELISA |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell motility |
Wound healing assay |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell motility |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell motility |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell motility |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell motility in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell motility in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell motility in presence of IL-6 |
Western Blot |
75.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell viability in presence of cisplatin |
SRB cell survival assay |
20.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on cell viability in presence of cisplatin |
SRB cell survival assay |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protin actiity in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
3,3 diindolylmethane |
Influence on protin actiity in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
STAT3 |
|
3,3 diindolylmethane |
Influence on protin actiity in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protin actiity in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protin actiity in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protin actiity in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein translocation in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
p-STAT3 (Y705) (nucleus) |
|
3,3 diindolylmethane |
Influence on protein translocation in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
STAT3 (nucleus) |
|
3,3 diindolylmethane |
Influence on protein translocation in presence of cisplatin |
Western Blot |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein-DNA interaction in presence of cisplatin |
Luciferase activity |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
STAT3 |
|
3,3 diindolylmethane |
Influence on cell motility in presence of cisplatin |
Aortic ring assay |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on VEGF secretion in presence of cisplatin |
ELISA |
50.00 µM |
SKOV-3 |
Homo sapiens |
|
|
|
3,3 diindolylmethane |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 mg |
SKOV-3 (xenografts) |
Mus musculus |
Crl:NU(NCr)-Foxn1nu |
|
|
3,3 diindolylmethane |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 mg |
SKOV-3 (xenografts) |
Mus musculus |
Crl:NU(NCr)-Foxn1nu |
|
|
3,3 diindolylmethane |
Influence on tumor growth in presence of cisplatin |
Tumor volume |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
3,3 diindolylmethane |
Influence on tumor growth in presence of cisplatin |
Mice weight |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
3,3 diindolylmethane |
Influence on tumor growth |
Tumor volume |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
3,3 diindolylmethane |
Influence on tumor growth |
Mice weight |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
3,3 diindolylmethane |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3 (Y705) |
|
3,3 diindolylmethane |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
3,3 diindolylmethane |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
3,3 diindolylmethane |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 mg/kg |
SKOV-3 (xenograft) |
Mus musculus |
athymic nude mice |
|
|