| OPB-31121 |
Influence on protein activity |
Western Blot |
1.00 µM |
HCT116 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
2.50 µM |
HCT116 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
5.00 µM |
HCT116 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
1.00 µM |
HCT116 |
Homo sapiens |
|
STAT3 |
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
2.50 µM |
HCT116 |
Homo sapiens |
|
STAT3 |
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
5.00 µM |
HCT116 |
Homo sapiens |
|
STAT3 |
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
1.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
2.50 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
5.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
1.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
2.50 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on protein activity |
Western Blot |
5.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
1.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
2.50 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
5.00 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on cell viability |
MTT |
7.50 µM |
HCT116 |
Homo sapiens |
|
|
|
| OPB-31121 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
p-STAT3 (Y705) |
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
STAT3 |
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
| OPB-31121 |
Influence on cell apoptosis |
TUNEL |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
STAT3 |
|
