CPA-7

Name	Value
Weight	0.000 g/mol
Zinc ID	N/A
Smiles	N/A
Molecular formula	N/A
Mode of inhibition	Direct STAT; targetting DBD
CAS	N/A

Clinical Trials

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References

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Publication	DOI	Pubmed	PMCID
CPA-7 influences immune profile and elicits anti-prostate cancer effects by inhibiting activated STAT3. BMC cancer Meihua Liang, Fei Zhan, Juan Zhao, Qi Li, Jiazi Wuyang, Guannan Mu, Dianjun Li, Yanqiao Zhang, Xiaoyi Huang, 16, None, 2016-07-19, 2016-07-19, 10.1186/s12885-016-2488-6	10.1186/s12885-016-2488-6	27435207	PMC4952363

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Filter data

Compound	CPA-7
Experiment types	Average survival, Body weight, Cell counting , Kaplan Meier recurence , Luciferase activity, Precentage of STAT3 cells, Tumor size , Western Blot
Concentrations	0.75, 1.50, 10.00, 20.00, 3.00, 5.00
Cell lines	RM-9
Organisms	Mus musculus
Animal models
STAT proteins	STAT3, p-STAT3 (Y705)
Other	Bcl-xL, β-tubulin

Experiments

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Compound	Experiment type	Investigated event	Concentration	Cell line	Organism	Animal model	Stat protein	Details
CPA-7	Body weight	Influence on tumor growth	0.75 mg/kg	RM-9	Mus musculus
CPA-7	Body weight	Influence on tumor growth	1.50 mg/kg	RM-9	Mus musculus
CPA-7	Body weight	Influence on tumor growth	3.00 mg/kg	RM-9	Mus musculus
CPA-7	Cell counting	Influence on tumor growth	5.00 µM	RM-9	Mus musculus
CPA-7	Cell counting	Influence on tumor growth	10.00 µM	RM-9	Mus musculus
CPA-7	Cell counting	Influence on tumor growth	20.00 µM	RM-9	Mus musculus
CPA-7	Tumor size	Influence on tumor growth	0.75 mg/kg	RM-9	Mus musculus
CPA-7	Tumor size	Influence on tumor growth	1.50 mg/kg	RM-9	Mus musculus
CPA-7	Kaplan Meier recurence	Influence on tumor growth	0.75 mg/kg	RM-9	Mus musculus
CPA-7	Kaplan Meier recurence	Influence on tumor growth	1.50 mg/kg	RM-9	Mus musculus

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