Andrographolide |
ELISA |
Influence on cytokine secretion |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cytokine secretion |
2.50 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cytokine secretion |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cytokine secretion |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cytokine secretion |
1.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cytokine secretion |
2.50 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cytokine secretion |
5.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cytokine secretion |
10.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level |
2.50 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
1.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
5.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
10.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
20.00 µM |
DU145 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
1.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
5.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
10.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
20.00 µM |
DU145 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
LNCaP |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
LNCaP |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
LNCaP |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
20.00 µM |
LNCaP |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
20.00 µM |
LNCaP |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
20.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
20.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
20.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
20.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
20.00 µM |
LNCaP |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
1.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
2.50 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
5.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
10.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
20.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
2.50 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
1.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
2.50 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
5.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
10.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
Trypan blue assay |
Influence on cell proliferation |
20.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
Invasion assay |
Influence on cell motility |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Invasion assay |
Influence on cell motility |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Invasion assay |
Influence on cell motility |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
Invasion assay |
Influence on cell motility |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
1.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
2.50 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
5.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
10.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
20.00 µM |
PC-3 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
1.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
2.50 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
5.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
10.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
20.00 µM |
DU145 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
1.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
2.50 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
5.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
10.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on cell apoptosis |
20.00 µM |
PzHPV-7 |
Homo sapiens |
|
|
|
Andrographolide |
Tumor volume |
Influence on cell proliferation in tumor tissue |
4.00 mg/kg |
DU145 (xenograft) |
Mus musculus |
nude mice |
|
|
Andrographolide |
Body weight |
Influence on cell proliferation in tumor tissue |
4.00 mg/kg |
DU145 (xenograft) |
Mus musculus |
nude mice |
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
5.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
100.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
100.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
5.00 µM |
Capan-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
10.00 µM |
Capan-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
25.00 µM |
Capan-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
50.00 µM |
Capan-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
100.00 µM |
Capan-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
5.00 µM |
BxPC-3 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
10.00 µM |
BxPC-3 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
25.00 µM |
BxPC-3 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
50.00 µM |
BxPC-3 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
100.00 µM |
BxPC-3 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
5.00 µM |
SW1990 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
10.00 µM |
SW1990 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
25.00 µM |
SW1990 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
50.00 µM |
SW1990 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
100.00 µM |
SW1990 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
5.00 µM |
L-02 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
10.00 µM |
L-02 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
25.00 µM |
L-02 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
50.00 µM |
L-02 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability |
100.00 µM |
L-02 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation |
5.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity |
50.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
25.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
CCK8 assay |
Influence on cell viability in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell proliferation in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Flow cytometry |
Influence on cell cycle in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of gemcitabine |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
Andrographolide |
Tumor volume |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
Andrographolide |
Tumor weight |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
Andrographolide |
Immunostaining |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
Andrographolide |
TUNEL |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
MTT Assay |
Influence on cell viability in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
MTT Assay |
Influence on cell viability in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
MTT Assay |
Influence on cell viability in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on nitrite and PGE2 secretion |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on nitrite and PGE2 secretion |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
ELISA |
Influence on nitrite and PGE2 secretion |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on apoptotic protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
p-STAT3 (Ser727) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
p-STAT3 (Ser727) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
p-STAT3 (Ser727) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level in presence of LPS |
50.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level in presence of LPS |
10.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
RT-qPCR |
Influence on mRNA expression level in presence of LPS |
2.00 µM |
RAW264.7 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Ser727) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
7.50 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
7.50 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Ser727) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
7.50 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity |
30.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
30.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Ser727) |
|
Andrographolide |
Western Blot |
Influence on protein activity |
30.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Luciferase activity |
Influence on protein activity |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
p-STAT3 (Tyr705); cytoplasm |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
p-STAT3 (Tyr705); nucleus |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
STAT3; cytoplasm |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
STAT3; nucleus |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of IL-6 |
15.00 µM |
HCT116 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Andrographolide |
Immunoprecipitation |
Influence on protein-protein interaction in presence of IL-6 |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:gp130 |
|
Andrographolide |
MTT Assay |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Andrographolide |
MTT Assay |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
HCT116 |
Homo sapiens |
|
|
|
Andrographolide |
MTT Assay |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Andrographolide |
MTT Assay |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
Hela |
Homo sapiens |
|
|
|
Andrographolide |
Crystal violet staining |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
HCT116 |
Homo sapiens |
|
|
|
Andrographolide |
Immunofluorescence |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
HCT116 |
Homo sapiens |
|
|
|
Andrographolide |
Immunofluorescence |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Andrographolide |
Immunofluorescence |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Andrographolide |
Immunofluorescence |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
Hela |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
Hela |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
Hela |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on cell apoptosis in presence of doxorubicin |
15.00 µM |
Hela |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of doxorubicin |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of doxorubicin |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of doxorubicin |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of doxorubicin |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Andrographolide |
Western Blot |
Influence on protein activity in presence of doxorubicin |
15.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|