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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Andrographolide Influence on cell proliferation in tumor tissue in presence of gemcitabine Tumor volume 15.00 mg/kg AsPC-1 (xenograft) Mus musculus BALB/c
Andrographolide Influence on cell proliferation in tumor tissue in presence of gemcitabine Tumor weight 15.00 mg/kg AsPC-1 (xenograft) Mus musculus BALB/c
Andrographolide Influence on cell proliferation in tumor tissue in presence of gemcitabine Immunostaining 15.00 mg/kg AsPC-1 (xenograft) Mus musculus BALB/c
Andrographolide Influence on cell proliferation in tumor tissue in presence of gemcitabine TUNEL 15.00 mg/kg AsPC-1 (xenograft) Mus musculus BALB/c
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Ser727)
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide Influence on protein activity Luciferase activity 15.00 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens p-STAT3 (Tyr705); cytoplasm
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens p-STAT3 (Tyr705); nucleus
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens STAT3; cytoplasm
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens STAT3; nucleus
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens
Andrographolide Influence on protein activity in presence of IL-6 Western Blot 15.00 µM HCT116 Homo sapiens
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens
Andrographolide Influence on protein activity Western Blot 15.00 µM MDA-MB-231 Homo sapiens
Andrographolide Influence on protein-protein interaction in presence of IL-6 Immunoprecipitation 15.00 µM MDA-MB-231 Homo sapiens STAT3:gp130
Andrographolide Influence on cell apoptosis in presence of doxorubicin MTT Assay 15.00 µM MDA-MB-231 Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin MTT Assay 15.00 µM HCT116 Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin MTT Assay 15.00 µM HepG2 Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin MTT Assay 15.00 µM Hela Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Crystal violet staining 15.00 µM HCT116 Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Immunofluorescence 15.00 µM HCT116 Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Immunofluorescence 15.00 µM MDA-MB-231 Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Immunofluorescence 15.00 µM HepG2 Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Immunofluorescence 15.00 µM Hela Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Western Blot 15.00 µM Hela Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Western Blot 15.00 µM Hela Homo sapiens
Andrographolide Influence on cell apoptosis in presence of doxorubicin Western Blot 15.00 µM Hela Homo sapiens
Andrographolide Influence on protein activity in presence of doxorubicin Western Blot 15.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Tyr705)
Andrographolide Influence on protein activity in presence of doxorubicin Western Blot 15.00 µM MDA-MB-231 Homo sapiens STAT3
Andrographolide Influence on protein activity in presence of doxorubicin Western Blot 15.00 µM MDA-MB-231 Homo sapiens
Andrographolide Influence on protein activity in presence of doxorubicin Western Blot 15.00 µM MDA-MB-231 Homo sapiens
Andrographolide Influence on protein activity in presence of doxorubicin Western Blot 15.00 µM MDA-MB-231 Homo sapiens