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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Arsenic trioxide Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens p-STAT3 (Tyr705)
Arsenic trioxide Influence on protein activity Western Blot 10.00 µM AGS Homo sapiens p-STAT3 (Tyr705)
Arsenic trioxide Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens STAT3
Arsenic trioxide Influence on protein activity Western Blot 10.00 µM AGS Homo sapiens STAT3
Arsenic trioxide Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity Western Blot 5.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell proliferation in presence of phosphatase inhibitor WST-1 Cell Proliferation Assay 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell motility in presence of phosphatase inhibitor Wound healing assay 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell motility in presence of phosphatase inhibitor Matrigel invasion assay 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell motility in presence of phosphatase inhibitor Spheroid cell invasion assay 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens p-STAT3 (Tyr705)
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens STAT3
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in presence of phosphatase inhibitor Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell proliferation in transfected cells Wound healing assay 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell motility in transfected cells Matrigel invasion assay 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell proliferation in transfected cells WST-1 Cell Proliferation Assay 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in transfected cells Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in transfected cells Western Blot 10.00 µM AGS Homo sapiens p-STAT3 (Tyr705)
Arsenic trioxide Influence on protein activity in transfected cells Western Blot 10.00 µM AGS Homo sapiens STAT3
Arsenic trioxide Influence on protein activity in transfected cells Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in transfected cells Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on protein activity in transfected cells Western Blot 10.00 µM AGS Homo sapiens
Arsenic trioxide Influence on cell proliferation in tumor tissue Tumor volume 2.00 mg/kg AGS (xenograft0 Mus musculus BALB/c athymin nude mice
Arsenic trioxide Influence on cell proliferation in tumor tissue Body weight 2.00 mg/kg AGS (xenograft0 Mus musculus BALB/c athymin nude mice
Arsenic trioxide Influence on cell proliferation in tumor tissue Immunohistochemistry 2.00 mg/kg AGS (xenograft0 Mus musculus BALB/c athymin nude mice
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 1.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 2.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 3.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 4.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 1.00 µM KG-1 Homo sapiens
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 2.00 µM KG-1 Homo sapiens
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 3.00 µM KG-1 Homo sapiens
Arsenic trioxide Influence on cell viability in presence of ruxolitinib MTT Assay 4.00 µM KG-1 Homo sapiens
Arsenic trioxide Influence on cell motility in presence of ruxolitinib Colony formation assay 2.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell motility in presence of ruxolitinib Colony formation assay 2.00 µM KG-1 Homo sapiens
Arsenic trioxide Influence on cell cycle in presence of ruxolitinib Flow cytometry 2.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell cycle in presence of ruxolitinib Flow cytometry 2.00 µM KG-1 Homo sapiens
Arsenic trioxide Influence on cell apoptosis in presence of ruxolitninib Flow cytometry- annexin V binding and propidium iodide staining 2.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell apoptosis in presence of ruxolitninib Flow cytometry- annexin V binding and propidium iodide staining 2.00 µM KG-1 Homo sapiens
Arsenic trioxide Influence on cell apoptosis in presence of ruxolitninib Immunofluorescence 2.00 µM U937 Homo sapiens
Arsenic trioxide Influence on cell apoptosis in presence of ruxolitninib Immunofluorescence 2.00 µM KG-1 Homo sapiens