| Andrographolide |
Influence on cell proliferation in presence of gemcitabine |
Crystal violet staining |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on cell proliferation in presence of gemcitabine |
Crystal violet staining |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on cell apoptosis in presence of gemcitabine |
Flow cytometry- annexin V binding and propidium iodide staining |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on cell apoptosis in presence of gemcitabine |
Flow cytometry- annexin V binding and propidium iodide staining |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on cell cycle in presence of gemcitabine |
Flow cytometry |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on cell cycle in presence of gemcitabine |
Flow cytometry |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on apoptotic and cell cycle protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
p-STAT3 (Tyr705) |
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
STAT3 |
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
STAT3 |
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
AsPC-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on protein activity in presence of gemcitabine |
Western Blot |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| Andrographolide |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
Tumor volume |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Andrographolide |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
Tumor weight |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Andrographolide |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
Immunostaining |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Andrographolide |
Influence on cell proliferation in tumor tissue in presence of gemcitabine |
TUNEL |
15.00 mg/kg |
AsPC-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
