| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
300.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
30.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
100.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in presence of IL-6 |
Western Blot |
300.00 nM |
Naïve CD4+ T |
Mus musculus |
c57BL/6 |
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
30.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
100.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
300.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
1000.00 nM |
HEK293T |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
30.00 nM |
HEK293T |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
100.00 nM |
HEK293T |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
300.00 nM |
HEK293T |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein activity in transfecfected cells |
Western Blot |
1000.00 nM |
HEK293T |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
30.00 nM |
FLS |
Homo sapiens |
|
p-STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
100.00 nM |
FLS |
Homo sapiens |
|
p-STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
300.00 nM |
FLS |
Homo sapiens |
|
p-STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
p-STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
30.00 nM |
FLS |
Homo sapiens |
|
STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
100.00 nM |
FLS |
Homo sapiens |
|
STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
300.00 nM |
FLS |
Homo sapiens |
|
STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
30.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
100.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
300.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
30.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
100.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
300.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
30.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
100.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
300.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of IL-6 |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on cytokine secretion in presence of IL-6 |
ELISA |
200.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on cytokine secretion in presence of IL-6 |
ELISA |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on mRNA expression |
Real-time TaqMan PCR |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on mRNA expression |
Real-time TaqMan PCR |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on mRNA expression |
Real-time TaqMan PCR |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on mRNA expression |
Real-time TaqMan PCR |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on cytokine secretion in presence of TNF |
ELISA |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on cytokine secretion in presence of TNF |
ELISA |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on cytokine secretion in presence of TNF |
ELISA |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on cytokine secretion in presence of TNF |
ELISA |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of TNF |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
p-STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of TNF |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
STAT1 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of TNF |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
p-STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of TNF |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
STAT3 |
|
| Tofacitinib (CP-690.550) |
Influence on protein acticity in presence of TNF |
Western Blot |
1000.00 nM |
FLS |
Homo sapiens |
|
|
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
| Withacnistin |
Influence on protein activity in presence of EGF |
Western Blot |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
p-STAT5A |
|
