| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
2.00 µM |
SH-SY5Y |
Homo sapiens |
|
STAT3 |
|
| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
5.00 µM |
SH-SY5Y |
Homo sapiens |
|
STAT3 |
|
| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
10.00 µM |
SH-SY5Y |
Homo sapiens |
|
STAT3 |
|
| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
20.00 µM |
SH-SY5Y |
Homo sapiens |
|
STAT3 |
|
| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
2.00 µM |
SH-SY5Y |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
5.00 µM |
SH-SY5Y |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
10.00 µM |
SH-SY5Y |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity in presence of bFGF |
Western Blot |
20.00 µM |
SH-SY5Y |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation in presence of Dox |
WST-8 |
1.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation in presence of Dox |
WST-8 |
1.00 µM |
SK-N-AS |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation in presence of Dox |
WST-8 |
1.00 µM |
LA-N6 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
SK-N-AS |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
SK-N-AS |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
SK-N-AS |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
SK-N-AS |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
SK-N-AS |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
LA-N6 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
LA-N6 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
LA-N6 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
LA-N6 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on apoptotic protein activity in presence of Dox |
Western Blot |
1.00 µM |
LA-N6 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on tumor growth |
Tumor size |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
p-STAT3 (Y705) |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
1.00 µM |
HEK293 |
Homo sapiens |
|
p-STAT3 |
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
2.00 µM |
HEK293 |
Homo sapiens |
|
p-STAT3 |
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
3.00 µM |
HEK293 |
Homo sapiens |
|
p-STAT3 |
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
1.00 µM |
HEK293 |
Homo sapiens |
|
STAT3 |
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
2.00 µM |
HEK293 |
Homo sapiens |
|
STAT3 |
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
3.00 µM |
HEK293 |
Homo sapiens |
|
STAT3 |
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
1.00 µM |
HEK293 |
Homo sapiens |
|
|
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
2.00 µM |
HEK293 |
Homo sapiens |
|
|
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
3.00 µM |
HEK293 |
Homo sapiens |
|
|
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
0.25 µM |
RAW 264.7 |
Mus musculus |
|
p-STAT3 (Tyr705) |
|
| inS3-54 |
Infleuence on protein activity |
Western Blot |
0.50 µM |
RAW 264.7 |
Mus musculus |
|
p-STAT3 (Tyr705) |
|
