| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
LIM2405 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
HT115 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
GEO |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
COLO320 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
LIM2537 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
HCA-7 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
COLO205 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
KM12 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
CCK81 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
SW620 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
SNU175 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
Cell Titer Glo assay |
1.00 µM |
C70 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell migration |
Wound healing assay |
1.00 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell migration |
Wound healing assay |
0.10 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell migration |
Wound healing assay |
0.50 µM |
DLD-1 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell migration |
Wound healing assay |
1.00 µM |
SW48 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell migration |
Wound healing assay |
0.10 µM |
SW48 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell migration |
Wound healing assay |
0.50 µM |
SW48 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on tumor growth |
Tumor volume |
10.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor volume |
30.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor volume |
10.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor volume |
30.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
10.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
30.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
10.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
30.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
10.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
30.00 mg/kg |
DLD-1 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
10.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
30.00 mg/kg |
SW48 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.05 µM |
IMR-32 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.50 µM |
IMR-32 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
1.00 µM |
IMR-32 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
5.00 µM |
IMR-32 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
10.00 µM |
IMR-32 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
20.00 µM |
IMR-32 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.05 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.50 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
1.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
5.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
10.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
20.00 µM |
NGP |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.05 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.50 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
1.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
5.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
20.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.05 µM |
SK-N-AS |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.50 µM |
SK-N-AS |
Homo sapiens |
|
|
|
