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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 1.25 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 1.25 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 20.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 5.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 2.50 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 1.25 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity in presence of pervanadate Western Blot 10.00 µM U251 Homo sapiens p-STAT3 (Y705)
Cryptotanshinone Influence on protein activity in presence of pervanadate Western Blot 10.00 µM U251 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity Western Blot 10.00 µM U251 Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-2 Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-2 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-2 Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-2 Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 5.00 µM U251 SHP-2 Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 5.00 µM U251 SHP-2 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 5.00 µM U251 SHP-2 Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 5.00 µM U251 SHP-2 Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 TC-PTP Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 TC-PTP Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 TC-PTP Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 TC-PTP Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-1 Homo sapiens p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-1 Homo sapiens STAT3
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-1 Homo sapiens
Cryptotanshinone Influence on protein activity in transfected cells Western Blot 10.00 µM U251 SHP-1 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue Average mice survival 30.00 mg/kg U87 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on cell proliferation in tumor tissue Average mice survival 60.00 mg/kg U87 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on cell proliferation in tumor tissue Tyrosine phosphatase activity 30.00 mg/kg U87 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on cell proliferation in tumor tissue Tyrosine phosphatase activity 60.00 mg/kg U87 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on protein activity in tumor tissue Immunohistochemistry 30.00 mg/kg U87 (xenograft) Mus musculus BALB/c p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in tumor tissue Immunohistochemistry 60.00 mg/kg U87 (xenograft) Mus musculus BALB/c p-STAT3(Y705)
Cryptotanshinone Influence on protein activity in tumor tissue Immunohistochemistry 30.00 mg/kg U87 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on protein activity in tumor tissue Immunohistochemistry 60.00 mg/kg U87 (xenograft) Mus musculus BALB/c
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 1.25 µM EC109 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 5.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 10.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 20.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 40.00 µM EC109 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 1.25 µM CAES17 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 5.00 µM CAES17 Homo sapiens
Cryptotanshinone Influence on cell proliferation in tumor tissue MTT Assay 10.00 µM CAES17 Homo sapiens