Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
1.25 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
5.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
1.25 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
20.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
5.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
2.50 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
1.25 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in presence of pervanadate |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
Cryptotanshinone |
Influence on protein activity in presence of pervanadate |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity |
Western Blot |
10.00 µM |
U251 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-2 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-2 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-2 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-2 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
5.00 µM |
U251 SHP-2 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
5.00 µM |
U251 SHP-2 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
5.00 µM |
U251 SHP-2 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
5.00 µM |
U251 SHP-2 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 TC-PTP |
Homo sapiens |
|
p-STAT3(Y705) |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 TC-PTP |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 TC-PTP |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 TC-PTP |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-1 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-1 |
Homo sapiens |
|
STAT3 |
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-1 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on protein activity in transfected cells |
Western Blot |
10.00 µM |
U251 SHP-1 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
Average mice survival |
30.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
Average mice survival |
60.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
Tyrosine phosphatase activity |
30.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
Tyrosine phosphatase activity |
60.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
|
|
Cryptotanshinone |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
30.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3(Y705) |
|
Cryptotanshinone |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
60.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
p-STAT3(Y705) |
|
Cryptotanshinone |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
30.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
|
|
Cryptotanshinone |
Influence on protein activity in tumor tissue |
Immunohistochemistry |
60.00 mg/kg |
U87 (xenograft) |
Mus musculus |
BALB/c |
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
1.25 µM |
EC109 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
5.00 µM |
EC109 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
10.00 µM |
EC109 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
20.00 µM |
EC109 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
40.00 µM |
EC109 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
1.25 µM |
CAES17 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
5.00 µM |
CAES17 |
Homo sapiens |
|
|
|
Cryptotanshinone |
Influence on cell proliferation in tumor tissue |
MTT Assay |
10.00 µM |
CAES17 |
Homo sapiens |
|
|
|