Investigated event: Influence on protien activity in tumor tissue

Name Value
Compound Homoharringtonine
Investigated event Influence on protien activity in tumor tissue
Experiment type Western Blot
Concentration 10.00 mg/kg
Cell line H1975 (xenograft)
Organism Mus musculus
Animal model
STAT protein
Other ERK1/2
Reference
Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Scientific reports Wei Cao, Ying Liu, Ran Zhang, Bo Zhang, Teng Wang, Xianbing Zhu, Lin Mei, Hongbo Chen, Hongling Zhang, Pinghong Ming, Laiqiang Huang, 5, None, 2015-07-13, 2015-07-13, 10.1038/srep08477 DOI: 10.1038/srep08477 PUBMED: 26166037 PMCID: PMC4499885