Niclosamide

Name Value
Weight 327.123 g/mol
Zinc ID ZINC3874496
Smiles O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O
Molecular formula C13H8Cl2N2O4
Mode of inhibition N/A
CAS 50-65-7

Clinical Trials

Study title Status Conditions Link
Effectiveness of Niclosamide as Add-on Therapy to the Standard of Care Measures in COVID-19 Management Recruiting Covid-19|SARS Pneumonia NCT04753619
Safety and Preliminary Efficacy of the Combination of Niclosamide and Camostat Terminated Covid19 NCT04750759
Safety and Pharmacokinetics of a Novel Niclosamide Solution in Combination With Camostat Completed Healthy Volunteers NCT04644705
A Study of Niclosamide Enemas in Subjects With Active Ulcerative Proctitis or Ulcerative Proctosigmoiditis Recruiting Ulcerative Colitis|Ulcerative Proctitis|Ulcerative Proctosigmoiditis NCT03521232
A Study of Niclosamide in Patients With Resectable Colon Cancer Terminated Colon Cancer NCT02687009
Niclosamide Role in Diabetic Nephropathy Recruiting Diabetic Nephropathies NCT04317430
Niclosamide for Familial Adenomatous Polyposis Recruiting Familial Adenomatous Polyposis NCT04296851
Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer Recruiting Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer NCT03123978
Single Ascending Dose and Multiple Ascending Dose Study of Niclosamide Inhalation Powder in Healthy Adult Subjects Recruiting Healthy NCT05168644
A Study To Evaluate The Efficacy And Safety Of a Novel Niclosamide Suspension Formulation For COVID-19 Recruiting Covid19 NCT04558021
Niclosamide for Mild to Moderate COVID-19 Completed COVID-19 NCT04399356
Niclosamide With Etanercept in Rheumatoid Arthritis Completed Rheumatoid Arthritis (RA) NCT03160001
Safety and Efficacy of Niclosamide in Patients With COVID-19 With Gastrointestinal Infection Recruiting Covid19 NCT04858425
Niclosamide and Enzalutamide in Treating Patients With Castration-Resistant, Metastatic Prostate Cancer Completed Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Adenocarcinoma NCT02532114
Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy Unknown status Colorectal Cancer NCT02519582
Niclosamide In Moderate COVID-19 Not yet recruiting COVID NCT04436458
Niclosamide in COVID-19 Not yet recruiting Covid19 NCT04542434
Abiraterone Acetate, Niclosamide, and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer Recruiting Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer NCT02807805
Hydroxychloroquine or Diltiazem-Niclosamide for the Treatment of COVID-19 Withdrawn Sars-CoV2 NCT04372082
A Single and Multiple Ascending Dose Study of Niclosamide in Healthy Volunteers Recruiting Healthy NCT04705415
Study of Niclosamide in Moderate and Severe Hospitalized Coronavirus-19 (COVID-19) Patients Recruiting COVID-19 NCT04603924
Safety and Efficacy of Intranasal Administration of Niclosamide (UNI91103) in Adults With Asymptomatic or Mild COVID-19 Recruiting Covid19 NCT04932915
Randomized-controlled Trial of the Effectiveness of COVID-19 Early Treatment in Community Recruiting Treatment Efficacy NCT05087381
PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V Recruiting Covid19 NCT04870333
Mass Treatment T Solium Community Study Terminated Intestinal Parasitism NCT00138359
To Assess the Safety, Tolerability and Pharmacokinetic Properties of Niclosamide Injectable (DWRX2003) Which is the Treatment of COVID-19 in Healthy Volunteers. Completed Covid19 NCT04749173
To Evaluate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of DWRX2003 Against COVID-19 Not yet recruiting Healthy NCT04524052
Targeted Screening for Taenia Solium Tapeworms Completed Taenia Solium Taeniasis NCT01296958
To Evaluate the Safety, Tolerability and Pharmacokinetic Properties of DWRX2003 Not yet recruiting COVID-19 Patients NCT04592835
Safety of Ascending Doses of Niclosamide (UNI911 INHALATION) in Healthy Volunteers Completed Covid19 NCT04576312
Clinical Evaluation - A Phase IIA Proof of Concept Study of Regorafenib (Bayer 73-4506) in Biopsy-amenable Asian Colorectal Cancer Patients Unknown status Asian Colorectal Cancer Patients NCT01189903
To Evaluate Safety, Tolerability and Pharmacodynamics of DWRX2003 Against COVID-19 (in Philippines) Terminated COVID-19 Patients NCT04541485

References

Publication DOI Pubmed PMCID
Spontaneous healing in paucibacillary leprosy. The Indian journal of medical research K Jesudasan, M Christian, 81, None, None, None, 10.1021/ml100146z 10.1021/ml100146z 4007964 PMC4007964
Control of ketogenesis and fatty-acid synthesis at the mitochondrial branch-point for acetyl-CoA in the chick liver cell: effect of adenosine 3',5'-monophosphate. European journal of biochemistry R A Mooney, M D Lane, 121, 2, None, None, 10.7150/jca.26948 10.7150/jca.26948 6277621 PMC6277621
Niclosamide reverses adipocyte induced epithelial-mesenchymal transition in breast cancer cells via suppression of the interleukin-6/STAT3 signalling axis. Scientific reports Jones Gyamfi, Yun-Hee Lee, Byung Soh Min, Junjeong Choi, 9, 1, 2019-08-05, 2019-08-05, 10.1038/s41598-019-47707-2 10.1038/s41598-019-47707-2 31383893 PMC6683291

Vendors

Company Lnk to product
Selleckchem https://www.selleckchem.com/products/niclosamide-niclocide.html
MERCK/Sigma Aldrich https://www.sigmaaldrich.com/PL/pl/product/sigma/n3510
MedKoo Biosciences https://www.medkoo.com/products/5674
Caymanchemicals https://www.caymanchem.com/product/10649/niclosamide
Tocris https://www.tocris.com/products/niclosamide_4079
APExBIO https://www.apexbt.com/niclosamide.html
ChemFaces https://www.chemfaces.com/natural/Niclosamide-CFN60348.html
Vitas-M Laboratory https://vitasmlab.biz/product_detail.php?chemid=9759605&stk=STK396676&qcode=niclosamide&pubchemid=0&url=locale
ChemScene https://www.chemscene.com/50-65-7.html
ANAWA https://www.anawa.ch/other-products-186/niclosamide-842000464.html
AK Scientific Inc. https://aksci.com/item_detail.php?cat=I012

Filter data

Compound Niclosamide
Experiment types CCK-8, Colony Formation , Colony formation assay , EMSA, Flow cytometry , Flow cytometry- annexin V FITC, Flow cytometry- annexin V staining, Hoechst 33342 staining, Live/Dead assay, Luciferase reporter assay , MTT, MTT Assay , RT-qPCR, TUNEL assay, Transwell Assay , Western Blot, Wound healing assay
Concentrations 0.10, 0.12, 0.20, 0.25, 0.50, 1.00, 10.00, 2.00, 20.00, 30.00, 4.00, 40.00, 5.00, 50.00, 6.00, 60.00, 70.00, 80.00, N/A
Cell lines DU145, Hela, HepG2, MCF-7, MDA-MB-468, MM1.S, PBMC, QGY-7703, SMMC-7721, U266
Organisms Homo sapiens
Animal models
STAT proteins STAT3, STAT3/DNA, p-STAT3, p-STAT3(Ser727), p-STAT3(Tyr705), p-STAT3(Y705)
Other Actin, Bcl-2, Bcl-xL, COx-2, Cyclin D1, E-Cadherin, GAPDH, IAP-1, Il-6, JAK1, JAK2, MMP-2, MMP-9, Mcl-1, Src, Survivin, VEGF, Vimentin, Zeb1, c-Myc, p-JAK1(Tyr1022/1023), p-JAK2(Tyr1007/1008), p-Src(Tyr416), p-Src(Tyr527), β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
Niclosamide MTT Influence on cell viability 5.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 10.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 20.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 30.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 40.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 50.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 60.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 70.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 80.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell viability 30.00 µM PBMC Homo sapiens
Niclosamide MTT Influence on cell viability 50.00 µM PBMC Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 30.00 µM PBMC Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 50.00 µM PBMC Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 30.00 µM PBMC Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 50.00 µM PBMC Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM PBMC Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM PBMC Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity in presence of IL-6 50.00 µM MM1.S Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity in presence of IL-6 50.00 µM MM1.S Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity in presence of pervanadate 50.00 µM MM1.S Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity in presence of pervanadate 50.00 µM MM1.S Homo sapiens STAT3
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 30.00 µM U266 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 50.00 µM U266 Homo sapiens
Niclosamide TUNEL assay Influence on cell apoptosis 30.00 µM U266 Homo sapiens
Niclosamide TUNEL assay Influence on cell apoptosis 50.00 µM U266 Homo sapiens
Niclosamide Live/Dead assay Influence on cell apoptosis 30.00 µM U266 Homo sapiens
Niclosamide Live/Dead assay Influence on cell apoptosis 50.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell proliferation 30.00 µM MM1.S Homo sapiens
Niclosamide MTT Influence on cell proliferation 50.00 µM MM1.S Homo sapiens
Niclosamide MTT Influence on cell proliferation 30.00 µM U266 Homo sapiens
Niclosamide MTT Influence on cell proliferation 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 30.00 µM U266 Homo sapiens
Niclosamide Western Blot Influence on protein activity 50.00 µM U266 Homo sapiens
Niclosamide RT-qPCR Influence on target gene expression 30.00 µM U266 Homo sapiens
Niclosamide RT-qPCR Influence on target gene expression 50.00 µM U266 Homo sapiens
Niclosamide RT-qPCR Influence on target gene expression 30.00 µM U266 Homo sapiens
Niclosamide RT-qPCR Influence on target gene expression 50.00 µM U266 Homo sapiens
Niclosamide RT-qPCR Influence on target gene expression 30.00 µM U266 Homo sapiens
Niclosamide RT-qPCR Influence on target gene expression 50.00 µM U266 Homo sapiens
Niclosamide Luciferase reporter assay Influence on protein activity N/A N/A Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.10 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.20 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.50 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 1.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 2.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 4.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 6.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 10.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Western Blot Influence on protein activity 4.00 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 6.00 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 10.00 µM Hela Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 4.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 6.00 µM Hela Homo sapiens
Niclosamide Western Blot Influence on protein activity 10.00 µM Hela Homo sapiens
Niclosamide EMSA Influence on protein translocation in presence of EGF 1.00 µM Hela Homo sapiens STAT3/DNA
Niclosamide EMSA Influence on protein translocation in presence of EGF 2.00 µM Hela Homo sapiens STAT3/DNA
Niclosamide EMSA Influence on protein translocation in presence of EGF 5.00 µM Hela Homo sapiens STAT3/DNA
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.10 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.20 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.50 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 1.00 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 2.00 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.10 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.20 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.50 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 1.00 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 2.00 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.10 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.20 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.50 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 1.00 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 2.00 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.10 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.20 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 0.50 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 1.00 µM DU145 Homo sapiens
Niclosamide Western Blot Influence on transcription of STAT3 downstrea targets 2.00 µM DU145 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell cycle 0.20 µM DU145 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell cycle 0.50 µM DU145 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell cycle 1.00 µM DU145 Homo sapiens
Niclosamide Flow cytometry Influence on cell apoptosis 1.00 µM DU145 Homo sapiens
Niclosamide Flow cytometry Influence on cell apoptosis 5.00 µM DU145 Homo sapiens
Niclosamide Flow cytometry Influence on cell apoptosis 10.00 µM DU145 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 1.00 µM HepG2 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 5.00 µM HepG2 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 10.00 µM HepG2 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 20.00 µM HepG2 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 1.00 µM QGY-7703 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 5.00 µM QGY-7703 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 10.00 µM QGY-7703 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 20.00 µM QGY-7703 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 1.00 µM SMMC-7721 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 5.00 µM SMMC-7721 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 10.00 µM SMMC-7721 Homo sapiens
Niclosamide MTT Assay Influence on cell viability 20.00 µM SMMC-7721 Homo sapiens
Niclosamide Colony formation assay Influence on cell proliferation 1.00 µM QGY-7703 Homo sapiens
Niclosamide Colony formation assay Influence on cell proliferation 5.00 µM QGY-7703 Homo sapiens
Niclosamide Colony formation assay Influence on cell proliferation 1.00 µM SMMC-7721 Homo sapiens
Niclosamide Colony formation assay Influence on cell proliferation 5.00 µM SMMC-7721 Homo sapiens
Niclosamide Colony formation assay Influence on cell proliferation 1.00 µM HepG2 Homo sapiens
Niclosamide Colony formation assay Influence on cell proliferation 5.00 µM HepG2 Homo sapiens
Niclosamide Flow cytometry- annexin V FITC Influence on cell apoptosis 5.00 µM HepG2 Homo sapiens
Niclosamide Hoechst 33342 staining Influence on cell apoptosis 5.00 µM SMMC-7721 Homo sapiens
Niclosamide Hoechst 33342 staining Influence on cell apoptosis 5.00 µM QGY-7703 Homo sapiens
Niclosamide Hoechst 33342 staining Influence on cell apoptosis 5.00 µM HepG2 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis in presence of cisplatin 5.00 µM QGY-7703 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis in presence of cisplatin 5.00 µM HepG2 Homo sapiens
Niclosamide Western Blot Influence on protein activity 5.00 µM QGY-7703 Homo sapiens p-STAT3
Niclosamide Western Blot Influence on protein activity 5.00 µM HepG2 Homo sapiens p-STAT3
Niclosamide Western Blot Influence on protein activity 5.00 µM HepG2 Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 5.00 µM HepG2 Homo sapiens
Niclosamide Western Blot Influence on protein activity 5.00 µM HepG2 Homo sapiens
Niclosamide Western Blot Influence on protein activity 5.00 µM HepG2 Homo sapiens
Niclosamide MTT Influence on cell viability N/A N/A MDA-MB-468 Homo sapiens
Niclosamide MTT Influence on cell viability N/A N/A MCF-7 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 0.12 µM MDA-MB-468 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 0.50 µM MDA-MB-468 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 1.00 µM MDA-MB-468 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 0.12 µM MCF-7 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 0.25 µM MCF-7 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 0.50 µM MCF-7 Homo sapiens
Niclosamide Flow cytometry- annexin V staining Influence on cell apoptosis 1.00 µM MCF-7 Homo sapiens
Niclosamide Wound healing assay Influence on cell motility 0.12 µM MDA-MB-468 Homo sapiens
Niclosamide Wound healing assay Influence on cell motility 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Wound healing assay Influence on cell motility 0.50 µM MDA-MB-468 Homo sapiens
Niclosamide Wound healing assay Influence on cell motility 0.12 µM MCF-7 Homo sapiens
Niclosamide Wound healing assay Influence on cell motility 0.25 µM MCF-7 Homo sapiens
Niclosamide Wound healing assay Influence on cell motility 0.50 µM MCF-7 Homo sapiens
Niclosamide CCK-8 Influence on cell proliferation 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide CCK-8 Influence on cell proliferation 0.25 µM MCF-7 Homo sapiens
Niclosamide Colony Formation Influence on cell proliferation 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Colony Formation Influence on cell proliferation 0.25 µM MCF-7 Homo sapiens
Niclosamide Transwell Assay Influence on cell proliferation 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Transwell Assay Influence on cell proliferation 0.25 µM MCF-7 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MCF-7 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MCF-7 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MCF-7 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MCF-7 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MDA-MB-468 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MCF-7 Homo sapiens
Niclosamide Western Blot Influence on protein activity 0.25 µM MDA-MB-468 Homo sapiens p-STAT3(Y705)
Niclosamide Western Blot Influence on protein activity 0.25 µM MCF-7 Homo sapiens p-STAT3(Y705)
Niclosamide Western Blot Influence on protein activity 0.25 µM MDA-MB-468 Homo sapiens STAT3
Niclosamide Western Blot Influence on protein activity 0.25 µM MCF-7 Homo sapiens STAT3