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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens STAT3
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens
Niclosamide Influence on protein translocation in presence of EGF EMSA 1.00 µM Hela Homo sapiens STAT3/DNA
Niclosamide Influence on transcription of STAT3 downstrea targets Western Blot 1.00 µM DU145 Homo sapiens
Niclosamide Influence on transcription of STAT3 downstrea targets Western Blot 1.00 µM DU145 Homo sapiens
Niclosamide Influence on transcription of STAT3 downstrea targets Western Blot 1.00 µM DU145 Homo sapiens
Niclosamide Influence on transcription of STAT3 downstrea targets Western Blot 1.00 µM DU145 Homo sapiens
Niclosamide Influence on cell cycle Flow cytometry- annexin V staining 1.00 µM DU145 Homo sapiens
Niclosamide Influence on cell apoptosis Flow cytometry 1.00 µM DU145 Homo sapiens
Niclosamide Influence on cell viability MTT Assay 1.00 µM HepG2 Homo sapiens
Niclosamide Influence on cell viability MTT Assay 1.00 µM QGY-7703 Homo sapiens
Niclosamide Influence on cell viability MTT Assay 1.00 µM SMMC-7721 Homo sapiens
Niclosamide Influence on cell proliferation Colony formation assay 1.00 µM QGY-7703 Homo sapiens
Niclosamide Influence on cell proliferation Colony formation assay 1.00 µM SMMC-7721 Homo sapiens
Niclosamide Influence on cell proliferation Colony formation assay 1.00 µM HepG2 Homo sapiens
Niclosamide Influence on cell apoptosis Flow cytometry- annexin V staining 1.00 µM MDA-MB-468 Homo sapiens
Niclosamide Influence on cell apoptosis Flow cytometry- annexin V staining 1.00 µM MCF-7 Homo sapiens