AG490 |
Western Blot |
Influence on protein activity in presence of IL-6 |
50.00 µM |
RT4 |
Homo sapiens |
|
p-STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of IL-6 |
50.00 µM |
RT4 |
Homo sapiens |
|
STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of IL-6 |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Luciferase promoter assay |
Influence on protein activity in presence of IL-6 |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of IL-6 |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of IL-6 |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
1.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
5.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
20.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
100.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
1.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
5.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
20.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
100.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
RT-PCR |
Influence on gene expression levels |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
RT-PCR |
Influence on gene expression levels |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein degradation |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of protease inhibitors |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of protease inhibitors |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein synthesis |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein synthesis |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influene on protein activity in presence of ER stress inducer |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influene on protein activity in presence of ER stress inducer |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influene on protein activity in presence of ER stress inducer |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on correlation between proetin levels and IL-6 response |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on correlation between proetin levels and IL-6 response |
50.00 µM |
RT4 |
Homo sapiens |
|
p-STAT3 |
|
AG490 |
Western Blot |
Influence on correlation between proetin levels and IL-6 response |
50.00 µM |
RT4 |
Homo sapiens |
|
STAT3 |
|
AG490 |
Western Blot |
Influence on correlation between proetin levels and IL-6 response |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of IFNγ |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
STAT1α |
|
AG490 |
Western Blot |
Influence on protein activity in presence of IFNγ |
100.00 µM |
1774 macrophages |
Homo sapiens |
|
STAT1α |
|
AG490 |
Griess reaction |
Influence on nitric oxide (NO) generation |
3.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
AG490 |
Griess reaction |
Influence on nitric oxide (NO) generation |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
AG490 |
Griess reaction |
Influence on nitric oxide (NO) generation |
30.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of IFNγ |
3.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of IFNγ |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of IFNγ |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of IFNγ |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT1 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT1 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT5 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT5 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
TUNEL |
Influence on EPO administration and apoptosis |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Hematoxylin and eosin staining |
Influence on EPO in ischemic quadriceps |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Immunohistochemical staining |
Influence on EPOR activity in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Laser Doppler |
Influence on blood flow recovery in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Immunohistochemical staining |
Influence on vessel density in presence of CLI and/or EPO |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
MMT |
Influence on cell viability |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
RT-qPCR |
Influence on gene expression levels |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Immunocytochemistry |
Influence on protein activity |
20.00 µM |
SW1990 |
Homo sapiens |
|
STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity |
20.00 µM |
SW1990 |
Homo sapiens |
|
p-STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity |
20.00 µM |
SW1990 |
Homo sapiens |
|
STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
Influence on protein activity |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Invasion assay |
Influence on cell motility |
20.00 µM |
SW1990 |
Homo sapiens |
|
|
|
AG490 |
Western Blot |
|
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
AG490 |
Western Blot |
|
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
RT-qPCR |
|
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
AG490 |
RT-qPCR |
|
25.00 μM/L |
Pancreatic Acinar Cells |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
AG490 |
Western Blot |
Influence on protein activity in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein activity in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein motility in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein motility in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein motility in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Western Blot |
Influence on protein motility in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
Immunofluorescence |
Influence on protein motility in presence of SAH |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
AG490 |
TUNEL |
Influence on neuronal apoptosis |
10.00 µM |
Brain tissue |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|