| AG490 |
Influence on nitric oxide (NO) generation |
Griess reaction |
3.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of IFNγ |
Western Blot |
3.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT1 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT1 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT3 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT5 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT5 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on EPO administration and apoptosis |
TUNEL |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on EPO in ischemic quadriceps |
Hematoxylin and eosin staining |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on gene expression levels in presence of CLI and/or EPO |
RT-qPCR |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on EPOR activity in presence of CLI and/or EPO |
Immunohistochemical staining |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on blood flow recovery in presence of CLI and/or EPO |
Laser Doppler |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
| AG490 |
Influence on vessel density in presence of CLI and/or EPO |
Immunohistochemical staining |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
