| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
5.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
10.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
2.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
5.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
10.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
2.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
5.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
10.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
2.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
5.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
10.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on dowstream target genes expression |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on cell apoptosis |
Flow cytometry |
20.00 µM |
Jurkat |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on cell apoptosis |
Flow cytometry |
20.00 µM |
SCC3 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on cell apoptosis |
Flow cytometry |
36.00 µM |
U937 |
Homo sapiens |
|
|
|
| STX-0119 |
Influence on protein translocation |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
p-STAT3 (nucleus) |
|
| STX-0119 |
Influence on protein translocation |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
p-STAT3 (cytoplasm) |
|
| STX-0119 |
Influence on protein translocation |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
STAT3 (nucelus) |
|
| STX-0119 |
Influence on protein translocation |
Western Blot |
20.00 µM |
SCC3 |
Homo sapiens |
|
STAT3 (cytoplam) |
|
| STX-0119 |
Influence on tumor growth |
Tumor volume |
40.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on tumor growth |
Tumor volume |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on tumor growth |
Body weight |
40.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on tumor growth |
Body weight |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
p-STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
p-STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
STAT3 |
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Hematoxylin and eosin staining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
p-STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
STAT3 |
|
| STX-0119 |
Influence on protein activity |
FRET |
10.00 µM |
HEK293 |
Homo sapiens |
|
STAT3-CFP |
|
| STX-0119 |
Influence on protein activity |
FRET |
20.00 µM |
HEK293 |
Homo sapiens |
|
STAT3-CFP |
|
| STX-0119 |
Influence on protein activity |
FRET |
50.00 µM |
HEK293 |
Homo sapiens |
|
STAT3-CFP |
|
| STX-0119 |
Influence on protein activity |
FRET |
10.00 µM |
HEK293 |
Homo sapiens |
|
STAT3-YFP |
|
| STX-0119 |
Influence on protein activity |
FRET |
20.00 µM |
HEK293 |
Homo sapiens |
|
STAT3-YFP |
|
| STX-0119 |
Influence on protein activity |
FRET |
50.00 µM |
HEK293 |
Homo sapiens |
|
STAT3-YFP |
|
| STX-0119 |
Influence on protein activity |
Chromatin immunoprecipitation |
10.00 µM |
MDA-MB-468 |
Homo sapiens |
|
STAT3 |
|
