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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
C188-9 Influence on cell viability and proliferation MTT 10.00 µM SCC-35 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 100.00 µM SCC-35 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 0.10 µM SCC-61 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 0.30 µM SCC-61 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 1.00 µM SCC-61 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 3.00 µM SCC-61 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 10.00 µM SCC-61 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 100.00 µM SCC-61 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 0.10 µM HN30 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 0.30 µM HN30 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 1.00 µM HN30 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 3.00 µM HN30 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 10.00 µM HN30 Homo sapiens
C188-9 Influence on cell viability and proliferation MTT 100.00 µM HN30 Homo sapiens
C188-9 Influence on tumor growth Tumor volume 50.00 mg/kg UM-SCC-17B(xengraft) Mus musculus nude
C188-9 Influence on tumor growth Western Blot 50.00 mg/kg UM-SCC-17B(xengraft) Mus musculus nude p-STAT3 (Tyr-705)
C188-9 Influence on tumor growth Western Blot 50.00 mg/kg UM-SCC-17B(xengraft) Mus musculus nude STAT3
C188-9 Influence on tumor growth Western Blot 50.00 mg/kg UM-SCC-17B(xengraft) Mus musculus nude
C188-9 Influence on tumor growth Western Blot 50.00 mg/kg UM-SCC-17B(xengraft) Mus musculus nude p-STAT1 (Tyr-701)
C188-9 Influence on tumor growth Western Blot 50.00 mg/kg UM-SCC-17B(xengraft) Mus musculus nude STAT1
C188-9 Level of STAT3 estimation Western Blot N/A N/A Hep-2 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Level of STAT3 estimation Western Blot N/A N/A Hep-2 Homo sapiens STAT3
C188-9 Level of STAT3 estimation Western Blot N/A N/A Hep-2 Homo sapiens
C188-9 Level of STAT3 estimation Western Blot N/A N/A CAL27 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Level of STAT3 estimation Western Blot N/A N/A CAL27 Homo sapiens STAT3
C188-9 Level of STAT3 estimation Western Blot N/A N/A CAL27 Homo sapiens
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC9 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC9 Homo sapiens STAT3
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC9 Homo sapiens
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC15 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC15 Homo sapiens STAT3
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC15 Homo sapiens
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC25 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC25 Homo sapiens STAT3
C188-9 Level of STAT3 estimation Western Blot N/A N/A SCC25 Homo sapiens
C188-9 Influence on proteins level Western Blot N/A N/A SCC15 Homo sapiens p-STAT1 (Tyr-701)
C188-9 Influence on proteins level Western Blot N/A N/A SCC15 Homo sapiens STAT1
C188-9 Influence on proteins level Western Blot N/A N/A SCC15 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Influence on proteins level Western Blot N/A N/A SCC15 Homo sapiens STAT3
C188-9 Influence on proteins level Western Blot N/A N/A SCC15 Homo sapiens
C188-9 Influence on proteins level Western Blot N/A N/A SCC25 Homo sapiens p-STAT1 (Tyr-701)
C188-9 Influence on proteins level Western Blot N/A N/A SCC25 Homo sapiens STAT1
C188-9 Influence on proteins level Western Blot N/A N/A SCC25 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Influence on proteins level Western Blot N/A N/A SCC25 Homo sapiens STAT3
C188-9 Influence on proteins level Western Blot N/A N/A SCC25 Homo sapiens
C188-9 Influence on nuclear translocation Western Blot N/A N/A SCC15 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Influence on nuclear translocation Western Blot N/A N/A SCC15 Homo sapiens
C188-9 Influence on nuclear translocation Western Blot N/A N/A SCC25 Homo sapiens p-STAT3 (Tyr-705)
C188-9 Influence on nuclear translocation Western Blot N/A N/A SCC25 Homo sapiens
C188-9 Influence on transcriptional activity Luciferase activity N/A N/A SCC15 Homo sapiens STAT3