| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
U251MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
U251MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
U251MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
U373MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
U373MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
U373MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
U251MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
U251MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
U251MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
U373MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
U373MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
U373MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
U251MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
U373MG |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
U251MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
U373MG |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
8.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
8.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
STAT3 |
|
| SH4-54 |
Influence on proetin acivity in presnce of EGF |
Western Blot |
10.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on proetin acivity in presnce of EGF |
Western Blot |
10.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
STAT3 |
|
| SH4-54 |
Influence on proetin acivity in presnce of EGF |
Western Blot |
10.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
|
|
| SH4-54 |
Influence on proetin acivity in presnce of EGF |
Western Blot |
10.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
|
|
| SH4-54 |
Influence on proetin acivity in presnce of EGF |
Western Blot |
10.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
|
|
| SH4-54 |
Influence on proetin acivity in presnce of EGF |
Western Blot |
10.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
|
|
| SH4-54 |
Influence on proetin acivity in presnce of EGF |
Western Blot |
10.00 µM |
NIH3T3/hEGFR |
Mus musculus |
|
|
|
| SH4-54 |
Influence on proetin acivity in presnce of IL-6 |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on proetin acivity in presnce of IL-6 |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Protein interaction with inhibitor |
Surface plasmon resonance analysis |
N/A N/A |
|
|
|
|
|
| SH4-54 |
Protein interaction with inhibitor |
NMR |
N/A N/A |
|
|
|
|
|
| SH4-54 |
Influence on protein binding to DNA |
EMSA |
8.00 µM |
U251MG |
Homo sapiens |
|
STAT3:STAT3 (nuclear) |
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
2.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
4.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
6.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
8.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
10.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
2.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
4.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
6.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
8.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
2.00 µM |
DU145 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
4.00 µM |
DU145 |
Homo sapiens |
|
|
|
