S3I-M2001 |
Influence on cell proliferation |
WST-1 |
150.00 µM |
MiaPaca-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
WST-1 |
200.00 µM |
MiaPaca-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
WST-1 |
250.00 µM |
MiaPaca-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
WST-1 |
300.00 µM |
MiaPaca-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
WST-1 |
350.00 µM |
MiaPaca-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
Colony formation assay |
30.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
Colony formation assay |
100.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
Colony formation assay |
30.00 µM |
NIH3T3/v-Ras |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
Colony formation assay |
100.00 µM |
NIH3T3/v-Ras |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
Colony formation assay |
30.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell proliferation |
Colony formation assay |
100.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on DNA |
TUNEL |
50.00 µM |
NIH3T3 |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on DNA |
TUNEL |
50.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on DNA |
TUNEL |
50.00 µM |
HUVEC |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on DNA |
TUNEL |
50.00 µM |
MDA-MB-453 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on DNA |
TUNEL |
50.00 µM |
MCF-10A |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on DNA |
TUNEL |
50.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on DNA |
TUNEL |
50.00 µM |
MDA-MB-435 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on apoptosis |
Flow cytometry |
50.00 µM |
3T3/v-Src/
pcDNA3 |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on apoptosis |
Flow cytometry |
50.00 µM |
3T3/v-Src/
ST3-SH2 |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on apoptosis |
Flow cytometry |
50.00 µM |
3T3/v-Src |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on apoptosis |
Western Blot |
50.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on apoptosis |
Western Blot |
50.00 µM |
MDA-MB-435 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on apoptosis |
Western Blot |
50.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on apoptosis |
Western Blot |
50.00 µM |
MDA-MB-435 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell motility |
Migration assay |
100.00 µM |
NIH3T3/v-Src |
Mus musculus |
|
|
|
S3I-M2001 |
Influence on cell motility |
Migration assay |
100.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on cell motility |
Migration assay |
100.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
S3I-M2001 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
S3I-M2001 |
Influence on tumor growth |
Tumor volume |
10.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
S3I-M2001 |
Influence on tumor growth |
Tumor volume |
20.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
S3I-M2001 |
Influence on DNA binding in tumor |
EMSA |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
STAT3:STAT3 |
|
S3I-M2001 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
STAT3 |
|
S3I-M2001 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
p-STAT3(Y705) |
|