| PG-S3-001 |
Inhibitor interaction with protein |
Fluorescence polarization competition assay |
0.01 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Fluorescence polarization competition assay |
0.10 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Fluorescence polarization competition assay |
10.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Fluorescence polarization competition assay |
100.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Fluorescence polarization competition assay |
1000.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Surface Plasmon Resonance |
0.01 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Surface Plasmon Resonance |
0.10 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Surface Plasmon Resonance |
10.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Surface Plasmon Resonance |
100.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Inhibitor interaction with protein |
Surface Plasmon Resonance |
1000.00 µM |
|
|
|
STAT3 |
|
| PG-S3-001 |
Influence on cell proliferation |
Alamar Blue assay |
N/A N/A |
Pa03C |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on cell proliferation |
Alamar Blue assay |
N/A N/A |
CAF19 |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on cytotoxicity |
MTS Assay |
6.25 µM |
Pa03C |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on cytotoxicity |
MTS Assay |
6.25 µM |
CAF19 |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on cytotoxicity |
MTS Assay |
6.25 µM |
CCD-13Lu |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
PaCa-2 |
Homo sapiens |
|
p-STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
PaCa-2 |
Homo sapiens |
|
p-STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
PaCa-2 |
Homo sapiens |
|
STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
PaCa-2 |
Homo sapiens |
|
STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
Pa02C |
Homo sapiens |
|
p-STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
Pa02C |
Homo sapiens |
|
p-STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
Pa02C |
Homo sapiens |
|
STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
Pa02C |
Homo sapiens |
|
STAT3 |
|
| PG-S3-001 |
Influence on protein activity in presence of IL-6 |
Western Blot |
4.00 µM |
CAF19 |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on cell proliferation |
Proliferation assay |
12.50 µM |
Pa03C (patient derived) |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on cell proliferation |
Proliferation assay |
25.00 µM |
Pa03C (patient derived) |
Homo sapiens |
|
|
|
| PG-S3-001 |
Influence on cell proliferation in tumor tissue |
Average weight |
10.00 mg/kg |
Pa03C (patient derived) |
Mus musculus |
NSG |
|
|
| PG-S3-001 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
10.00 mg/kg |
Pa03C (patient derived) |
Mus musculus |
NSG |
|
|
