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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
OPB-31121 Infleunce on protein activity Western Blot 0.50 nM DU145 Homo sapiens STAT3
OPB-31121 Infleunce on protein activity Western Blot 1.00 nM DU145 Homo sapiens STAT3
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens STAT3
OPB-31121 Infleunce on protein activity Western Blot 10.00 nM DU145 Homo sapiens STAT3
OPB-31121 Infleunce on protein activity Western Blot 50.00 nM DU145 Homo sapiens STAT3
OPB-31121 Infleunce on protein activity Western Blot 100.00 nM DU145 Homo sapiens STAT3
OPB-31121 Infleunce on protein activity Western Blot 0.50 nM DU145 Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity Western Blot 1.00 nM DU145 Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity Western Blot 10.00 nM DU145 Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity Western Blot 50.00 nM DU145 Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity Western Blot 100.00 nM DU145 Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity Western Blot 0.50 nM DU145 Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity Western Blot 1.00 nM DU145 Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity Western Blot 10.00 nM DU145 Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity Western Blot 50.00 nM DU145 Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity Western Blot 100.00 nM DU145 Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity Western Blot 0.50 nM DU145 Homo sapiens
OPB-31121 Infleunce on protein activity Western Blot 1.00 nM DU145 Homo sapiens
OPB-31121 Infleunce on protein activity Western Blot 5.00 nM DU145 Homo sapiens
OPB-31121 Infleunce on protein activity Western Blot 10.00 nM DU145 Homo sapiens
OPB-31121 Infleunce on protein activity Western Blot 50.00 nM DU145 Homo sapiens
OPB-31121 Infleunce on protein activity Western Blot 100.00 nM DU145 Homo sapiens
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 1.00 nM LNCaP Homo sapiens STAT3
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens STAT3
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 10.00 nM LNCaP Homo sapiens STAT3
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 50.00 nM LNCaP Homo sapiens STAT3
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 1.00 nM LNCaP Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 10.00 nM LNCaP Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 50.00 nM LNCaP Homo sapiens p-STAT3 (Y705)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 1.00 nM LNCaP Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 10.00 nM LNCaP Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 50.00 nM LNCaP Homo sapiens p-STAT3 (S727)
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 1.00 nM LNCaP Homo sapiens
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 5.00 nM LNCaP Homo sapiens
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 10.00 nM LNCaP Homo sapiens
OPB-31121 Infleunce on protein activity in presence of IL-6 Western Blot 50.00 nM LNCaP Homo sapiens
OPB-31121 Influence on cell proliferation MTT 0.03 µM DU145 Homo sapiens
OPB-31121 Influence on cell proliferation MTT 0.03 µM LNCaP Homo sapiens
OPB-31121 Influence on cell proliferation Colony formation assay 10.00 nM DU145 Homo sapiens
OPB-31121 Influence on cell proliferation Colony formation assay 50.00 nM DU145 Homo sapiens
OPB-31121 Influence on cell proliferation Colony formation assay 10.00 nM LNCaP Homo sapiens
OPB-31121 Influence on cell proliferation Colony formation assay 50.00 nM LNCaP Homo sapiens
OPB-31121 Influence on cell proliferation MTT 0.30 nM SNU484 Homo sapiens
OPB-31121 Influence on cell proliferation MTT 1.00 nM SNU484 Homo sapiens
OPB-31121 Influence on cell proliferation MTT 3.00 nM SNU484 Homo sapiens
OPB-31121 Influence on cell proliferation MTT 10.00 nM SNU484 Homo sapiens