| Momelotinib (CYT387) |
Influence on STAT3 activity in presence of IL6 |
Flow cytometry |
1.50 µM |
CLBL-1 |
Canis familriaris |
|
p-STAT3 |
|
| Momelotinib (CYT387) |
Influence on STAT3 activity in presence of IL6 |
MFI |
1.50 µM |
CLBL-1 |
Canis familriaris |
|
p-STAT3 |
|
| Momelotinib (CYT387) |
Influence on cell apoptosis |
Flow cytometry |
1.00 µM |
CLBL-1 |
Canis familriaris |
|
|
|
| Momelotinib (CYT387) |
Influence on cell apoptosis |
Flow cytometry |
5.00 µM |
CLBL-1 |
Canis familriaris |
|
|
|
| Momelotinib (CYT387) |
Influence on cell apoptosis |
Flow cytometry |
1.00 µM |
MDCK |
Canis familriaris |
|
|
|
| Momelotinib (CYT387) |
Influence on cell apoptosis |
Flow cytometry |
5.00 µM |
MDCK |
Canis familriaris |
|
|
|
| Momelotinib (CYT387) |
Influence on cell cycle |
Ki67/DAPI cell proliferation assay |
1.00 µM |
CLBL-1 |
Canis familriaris |
|
|
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
p-STAT1 |
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
STAT1 |
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
p-STAT3 |
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
STAT3 |
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
p-STAT5 |
|
| Momelotinib (CYT387) |
Influence on protein activity in response to TSLP stimulation |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
STAT5 |
|
| Momelotinib (CYT387) |
Influence on surface protein |
Flow cytometry |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on surface protein |
Flow cytometry |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on surface protein |
Flow cytometry |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on surface protein |
Flow cytometry |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on surface protein |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on surface protein |
RT-PCR |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on inflammatory Th2 cell response |
Flow cytometry |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on Th2 response |
Histopathological staining |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on Th2 response |
Western Blot |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on Th2 response |
Western Blot |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISPOT |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISPOT |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
