| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on gene expression |
RT-PCR |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in presence of IFNγ |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
p-STAT1 (Y701) |
|
| LLL-12 |
Influence on protein activity in presence of IFNγ |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
p-STAT1 (Y701) |
|
| LLL-12 |
Influence on protein activity in presence of IFNγ |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
STAT1 |
|
| LLL-12 |
Influence on protein activity in presence of IFNγ |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
STAT1 |
|
| LLL-12 |
Influence on protein activity in presence of IFNγ |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on protein activity in presence of IFNγ |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
2.50 µM |
U2OS |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
10.00 µM |
U2OS |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
2.50 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
5.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
2.50 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell proliferation |
Focus formation |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
2.50 µM |
U2OS |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
10.00 µM |
U2OS |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
2.50 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
5.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
2.50 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on cell migration |
Wound healing assay |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
| LLL-12 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
OS-33 (xenograft) |
Mus musculus |
|
|
|
| LLL-12 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
|
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
|
|
