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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
LLL-12 Influence on protein activity Western Blot 10.00 µM SNU387 Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SNU398 Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SNU398 Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SNU449 Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SNU449 Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM Hep3B Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM Hep3B Homo sapiens
LLL-12 Influence on cell cycle Flow cytometry 5.00 µM SNU387 Homo sapiens
LLL-12 Influence on cell cycle Flow cytometry 5.00 µM SNU398 Homo sapiens
LLL-12 Influence on cell cycle Flow cytometry 5.00 µM SNU449 Homo sapiens
LLL-12 Influence on cell cycle Flow cytometry 5.00 µM Hep3B Homo sapiens
LLL-12 Influence on protein activity Immunofluorescence staining 5.00 µM SNU387 Homo sapiens p-STAT3
LLL-12 Influence on protein activity Immunofluorescence staining 5.00 µM SNU398 Homo sapiens p-STAT3
LLL-12 Influence on tumor growth Tumor volume 5.00 mg/kg SNU398 (xenograft) Mus musculus nude mice
LLL-12 Influence on tumor growth Body weight 5.00 mg/kg SNU398 (xenograft) Mus musculus nude mice
LLL-12 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SAOS2 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SAOS2 Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 5.00 µM SAOS2 Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SAOS2 Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SAOS2 Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SAOS2 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SAOS2 Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 10.00 µM SAOS2 Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SAOS2 Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SAOS2 Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM HSMM Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM HSMM Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 5.00 µM HSMM Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM HSMM Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM HSMM Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM HSMM Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 10.00 µM HSMM Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM HSMM Homo sapiens
LLL-12 Influence on cell apoptosis Flow cytometry 10.00 µM SAOS2 Homo sapiens
LLL-12 Influence on cell apoptosis Flow cytometry 10.00 µM SJSA Homo sapiens
LLL-12 Influence on gene expression RT-PCR 10.00 µM SAOS2 Homo sapiens